Sildenafil/Clomipramine Combo Boosts Outcomes in Premature Ejaculation

Say a man lasts a few

• Some medications are designed specifically for premature ejaculation.
• Using pills without medical advice risks adverse effects.
• Combining pills with behavioral techniques can yield better results.
• Natural pills often lack scientific evidence for efficacy.
• Regular follow-up with a healthcare provider is crucial.

seconds to half-a-minute on his own.

Warning: Watch out for unreliable pills

The Little-Known Downsides of PE Medication The drugs used to treat PE belong to the most popular class of antidepressants: selective serotonin reuptake inhibitors (SSRIs) such as Prozac, Zoloft, Paxil, Lexapro, Luvox, Celexa, Viibri, and Brintellix. But soon after the FDA’s 1987 approval of the first SSRI, Prozac, it became clear that the SSRIs have a side effect—delay of orgasm, and possibly loss of ability to climax at all. Drug makers discovered that in men with PE, lowering the dose could delay but not totally suppress orgasm/ejaculation. Several analyses of low-dose SSRIs show the drugs help men last one to five minutes longer. The review authors call this “significant effectiveness.” Actually, that’s an exaggeration that borders on medical irresponsibility.