Sildenafil Citrate Oral Suspension for Managing Erectile Dysfunction: A Systematic Review and a Consensus Report from the Italian Society of Andrology (SIA)
For pulmonary arterial hypertension:Take or administer the prescribed dose three times a day, four to six hours apart.
Recent Updates on Sildenafil Research
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers.
When and How to Take Sildenafil for Best Results
Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays).
Erectile Dysfunction
Pharmacy names, logos, brands, and other trademarks are the property of their respective owners. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911. If you are a consumer or patient please visit this version. Take or administer the prescribed dose three times a day, four to six hours apart. How to take sildenafil oral suspension for pulmonary hypertension:Please read and follow the Instructions for Use.Do not use the medicine if it’s still in powder form, doesn’t have a bottle adapter, or is missing an oral syringe. The pharmacist can provide a bottle adapter or oral syringe.Shake the bottle well for at least 10 seconds.Always measure the dose with the oral syringe provided in the package.Do not mix the dose with other liquids or flavorings.The person getting the medicine should be upright.Place the syringe in the mouth against the cheek.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Viagra Generic | 50mg | 180 + 8 Pills | 158.82€ 151.26€ | |
| Viagra Generic | 100mg | 120 + 6 Pills | 149.50€ 142.38€ | |
| Viagra Generic | 200mg | 60 + 4 Pills | 125.19€ 119.23€ | |
| Kamagra | 100mg | 120 + 6 Pills | 330.74€ 314.99€ | |
| Viagra Generic | 150mg | 90 + 6 Pills | 147.18€ 140.17€ | |
| Viagra Generic | 150mg | 60 + 4 Pills | 111.25€ 105.95€ | |
| Kamagra | 100mg | 60 + 4 Pills | 201.34€ 191.75€ | |
| Viagra Generic | 25mg | 360 + 10 Pills | 213.68€ 203.50€ | |
| Viagra Generic | 100mg | 10 Pills | 28.91€ 27.53€ | |
| Viagra Generic | 50mg | 60 + 4 Pills | 83.93€ 79.93€ |
Push the plunger completely down.Wash the syringe with water and allow it to dry after each use.Store sildenafil oral suspension in the refrigerator. Do not freeze.Throw away any unused medicine 60 days after receiving it from the pharmacist or on the expiration date written on the bottle’s label. How to take sildenafil oral suspension for pulmonary hypertension: Please read and follow the Instructions for Use. Please read and follow the Instructions for Use. Do not use the medicine if it’s still in powder form, doesn’t have a bottle adapter, or is missing an oral syringe. The pharmacist can provide a bottle adapter or oral syringe.
Get your FREE Drugs.com Discount Card
HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use SILDENAFIL INJECTION safely and effectively. See full prescribing information for SILDENAFIL INJECTION.SILDENAFIL injection, for intravenous useInitial U.S. Approval: 1998INDICATIONS AND USAGEAdultsSildenafil injection is a phosphodiesterase-5 (PDE-5) inhibitor indicated for the treatment of pulmonary arterial hypertension (PAH) (World Health Organization [WHO] Group I) in adults to improve exercise ability and delay clinical worsening. (1)DOSAGE AND ADMINISTRATIONInjection (Adults): 10 mg three times a day administered as an intravenous bolus injection (2.1)DOSAGE FORMS AND STRENGTHSInjection: 10 mg/12.5 mL in a single-dose vial (3)CONTRAINDICATIONSWARNINGS AND PRECAUTIONSVasodilation effects may be more common in patients with hypotension or on antihypertensive therapy. (5.1)Use in pulmonary veno-occlusive disease (PVOD) may cause pulmonary edema and is not recommended. Shake the bottle well for at least 10 seconds. Always measure the dose with the oral syringe provided in the package. Do not mix the dose with other liquids or flavorings. The person getting the medicine should be upright. Place the syringe in the mouth against the cheek. Wash the syringe with water and allow it to dry after each use. Store sildenafil oral suspension in the refrigerator. Throw away any unused medicine 60 days after receiving it from the pharmacist or on the expiration date written on the bottle’s label. In clinical trials, sildenafil showed significant effects on erectile response 60 minutes after the dose was taken, though the effects may be evident within 30 minutes. For pulmonary hypertension, sildenafil lowers blood pressure about one to two hours after a dose is taken. With a half-life of four hours, sildenafil and its active metabolite are completely cleared from the system in about 20 hours, though the effects fade before then. For erectile dysfunction, sildenafil produces its maximum effects for about two hours and can still produce an erectile response four hours after a dose is taken.
| Condition | Reason | Alternative Action |
|---|---|---|
| Use of Nitrates | Risk of severe hypotension | Consult doctor for alternatives |
| Severe Cardiovascular Disease | Increased risk during physical exertion | Adjust dosage or avoid use |
| Retinitis Pigmentosa | Possible risk of vision loss | Medical consultation |
| Hypersensitivity | Allergic reaction risk | Do not use |
For pulmonary hypertension, sildenafil’s benefits in lowering blood pressure were the same as a placebo (inert pill) after eight hours. For treatment of erectile dysfunction, take only one dose per day.
| Study Name | Sample Size | Success Rate | Main Findings |
|---|---|---|---|
| Randomized Trial A | 200 | 70% | Significant improvement in erectile function |
| Clinical Study B | 150 | 65% | Efficacy maintained at 12.5 mg dose |
| Comparative Study C | 100 | 75% | Similar results to higher doses but fewer side effects |
If a dose has been forgotten, take it when remembered but wait at least 30 minutes before attempting sexual activity. For pulmonary hypertension, take a missed dose as soon as you remember it. If it’s almost time for the next dose, skip the missed dose and take the next dose as scheduled. If too much sildenafil is taken, get immediate medical attention. Side effects of sildenafil, such as headache, flushing, stomach upset, nasal congestion, back pain, low blood pressure, or painful erections (priapism), are more likely and could be worse than normal. Serious side effects are also possible such as heart rate problems, chest pain (angina), and heart attack. Do not take sildenafil if you are using medications called nitrates, such as nitroglycerin, or over-the-counter nitrites (“poppers”), such as amyl nitrite.
- Sildenafil 12.5 mg can improve confidence and quality of life.
- Patients should discuss potential drug interactions with their doctor.
- Be aware of potential side effects and report unusual symptoms promptly.
Sildenafil should also never be combined with heart failure drugs called guanylate cyclase stimulators (riociguat or vericiguat). Make sure the prescriber knows about all drugs and substances you use, including vitamins, supplements, and illicit substances. To avoid more serious drug interactions, the prescriber will need to know about: Other ED drugs or supplements, particularly Cialis (tadalafil) or vardenafil Other ED drugs or supplements, particularly Cialis (tadalafil) or vardenafil HIV/AIDS drugs called protease inhibitors, especially ritonavir HIV/AIDS drugs called protease inhibitors, especially ritonavir Oral antifungal drugs such as ketoconazole or itraconazole Oral antifungal drugs such as ketoconazole or itraconazole To reduce the risk of side effects, avoid drinking grapefruit juice when taking sildenafil. Although there isn’t much information about the safety of sildenafil during pregnancy, animal studies have shown no adverse effects on a fetus. Pregnant women or women who are breastfeeding should ask for medical advice before taking sildenafil.
Sildenafil in Pregnancy
(5.2)Hearing or visual impairment: Seek medical attention if sudden decrease or loss of vision or hearing occurs. (5.4, 5.5)Pulmonary hypertension (PH) secondary to sickle cell disease: Sildenafil may cause serious vaso-occlusive crises. (5.8)ADVERSE REACTIONSDRUG INTERACTIONSUse with strong CYP3A inhibitors: Not recommended. (7, 12.3)Concomitant PDE-5 inhibitors: Avoid use with Viagra® or other PDE-5 inhibitors. Plumb’s Veterinary Drug Manual, 7 edition Plumb’s Veterinary Drug Manual, 7 edition Revatio prescribing information, DailyMed (NIH National Library of Medicine) Revatio prescribing information, DailyMed (NIH National Library of Medicine) Sildenafil citrate powder for oral suspension prescribing information, DailyMed (NIH National Library of Medicine) Sildenafil citrate powder for oral suspension prescribing information, DailyMed (NIH National Library of Medicine) Systemic and pulmonary hypertension in dogs and cats, Merck Veterinary Manual Systemic and pulmonary hypertension in dogs and cats, Merck Veterinary Manual Viagra drug summary, Prescriber’s Digital Reference (PDR) Viagra drug summary, Prescriber’s Digital Reference (PDR) Viagra sildenafil citrate tablet prescribing information, DailyMed (NIH National Library of Medicine) Viagra sildenafil citrate tablet prescribing information, DailyMed (NIH National Library of Medicine) Jessica Swirble, Pharm.D., is a 2007 graduate of the Philadelphia College of Pharmacy and has more than 16 years of experience as a pharmacist. She currently resides in Pennsylvania and works as a community pharmacist.
Patient Assistance & Copay Programs for Sildenafil
Wash the syringe with water and allow it to dry after each use. Store sildenafil oral suspension in the refrigerator. Throw away any unused medicine 60 days after receiving it from the pharmacist or on the expiration date written on the bottle’s label. In clinical trials, sildenafil showed significant effects on erectile response 60 minutes after the dose was taken, though the effects may be evident within 30 minutes. For pulmonary hypertension, sildenafil lowers blood pressure about one to two hours after a dose is taken.
Postmarketing Reports
With a half-life of four hours, sildenafil and its active metabolite are completely cleared from the system in about 20 hours, though the effects fade before then. For erectile dysfunction, sildenafil produces its maximum effects for about two hours and can still produce an erectile response four hours after a dose is taken. For pulmonary hypertension, sildenafil’s benefits in lowering blood pressure were the same as a placebo (inert pill) after eight hours. For treatment of erectile dysfunction, take only one dose per day. If a dose has been forgotten, take it when remembered but wait at least 30 minutes before attempting sexual activity.
Allergy warning
For pulmonary hypertension, take a missed dose as soon as you remember it. If it’s almost time for the next dose, skip the missed dose and take the next dose as scheduled. If too much sildenafil is taken, get immediate medical attention. Side effects of sildenafil, such as headache, flushing, stomach upset, nasal congestion, back pain, low blood pressure, or painful erections (priapism), are more likely and could be worse than normal. Serious side effects are also possible such as heart rate problems, chest pain (angina), and heart attack. She is also a freelance sildenafil 25mg tablets medical writer and reviewer. When away from work, she enjoys traveling, baking, reading, and spending time with her family. By clicking 'Subscribe', I agree to SingleCare's Terms & Conditions. SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. It can be used whether you have insurance, Medicare, Medicaid, or none of the above, but it cannot be combined with insurance. SingleCare provides transparent drug pricing, so you can compare discounts at pharmacies near you. Browse singlecare.com to find drug discounts, helpful information about your prescription, and resources to help you make informed health decisions. Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060.
5.7 Priapism
Do not take sildenafil if you are using medications called nitrates, such as nitroglycerin, or over-the-counter nitrites (“poppers”), such as amyl nitrite. Sildenafil should also never be combined with heart failure drugs called guanylate cyclase stimulators (riociguat or vericiguat). Make sure the prescriber knows about all drugs and substances you use, including vitamins, supplements, and illicit substances. To avoid more serious drug interactions, the prescriber will need to know about: Other ED drugs or supplements, particularly Cialis (tadalafil) or vardenafil Other ED drugs or supplements, particularly Cialis (tadalafil) or vardenafil HIV/AIDS drugs called protease inhibitors, especially ritonavir HIV/AIDS drugs called protease inhibitors, especially ritonavir Oral antifungal drugs such as ketoconazole or itraconazole Oral antifungal drugs such as ketoconazole or itraconazole To reduce the risk of side effects, avoid drinking grapefruit juice when taking sildenafil. Although there isn’t much information about the safety of sildenafil during pregnancy, animal studies have shown no adverse effects on a fetus.
How sildenafil is used
Pregnant women or women who are breastfeeding should ask for medical advice before taking sildenafil. Plumb’s Veterinary Drug Manual, 7 edition Plumb’s Veterinary Drug Manual, 7 edition Revatio prescribing information, DailyMed (NIH National Library of Medicine) Revatio prescribing information, DailyMed (NIH National Library of Medicine) Sildenafil citrate powder for oral suspension prescribing information, DailyMed (NIH National Library of Medicine) Sildenafil citrate powder for oral suspension prescribing information, DailyMed (NIH National Library of Medicine) Systemic and pulmonary hypertension in dogs and cats, Merck Veterinary Manual Systemic and pulmonary hypertension in dogs and cats, Merck Veterinary Manual Viagra drug summary, Prescriber’s Digital Reference (PDR) Viagra drug summary, Prescriber’s Digital Reference (PDR) Viagra sildenafil citrate tablet prescribing information, DailyMed (NIH National Library of Medicine) Viagra sildenafil citrate tablet prescribing information, DailyMed (NIH National Library of Medicine) Jessica Swirble, Pharm.D., is a 2007 graduate of the Philadelphia College of Pharmacy and has more than 16 years of experience as a pharmacist. She currently resides in Pennsylvania and works as a community pharmacist. She is also a freelance sildenafil 25mg tablets medical writer and reviewer. When away from work, she enjoys traveling, baking, reading, and spending time with her family.
Heart Failure (Off-Label Use)
By clicking 'Subscribe', I agree to SingleCare's Terms & Conditions. SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. It can be used whether you have insurance, Medicare, Medicaid, or none of the above, but it cannot be combined with insurance. SingleCare provides transparent drug pricing, so you can compare discounts at pharmacies near you. Browse singlecare.com to find drug discounts, helpful information about your prescription, and resources to help you make informed health decisions. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays).
- Store sildenafil at room temperature, away from moisture and heat.
- Keep out of reach of children and pets.
- Do not use expired medication; freshness ensures safety and efficacy.
Pharmacy names, logos, brands, and other trademarks are the property of their respective owners. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment.
| Point | Explanation | Advice |
|---|---|---|
| Timing for ingestion | Take 30-60 minutes before sexual activity | Avoid late ingestion |
| Alcohol consumption | May increase side effects | Limited alcohol intake |
| Food intake | Can be taken with or without food | Avoid high-fat meals for quicker onset |
| Adherence to prescribed dose | Important for safety and efficacy | Follow doctor's instructions |
Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911. If you are a consumer or patient please visit this version. HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use SILDENAFIL INJECTION safely and effectively. See full prescribing information for SILDENAFIL INJECTION.SILDENAFIL injection, for intravenous useInitial U.S. Approval: 1998INDICATIONS AND USAGEAdultsSildenafil injection is a phosphodiesterase-5 (PDE-5) inhibitor indicated for the treatment of pulmonary arterial hypertension (PAH) (World Health Organization [WHO] Group I) in adults to improve exercise ability and delay clinical worsening. (1)DOSAGE AND ADMINISTRATIONInjection (Adults): 10 mg three times a day administered as an intravenous bolus injection (2.1)DOSAGE FORMS AND STRENGTHSInjection: 10 mg/12.5 mL in a single-dose vial (3)CONTRAINDICATIONSWARNINGS AND PRECAUTIONSVasodilation effects may be more common in patients with hypotension or on antihypertensive therapy. (5.1)Use in pulmonary veno-occlusive disease (PVOD) may cause pulmonary edema and is not recommended. (5.2)Hearing or visual impairment: Seek medical attention if sudden decrease or loss of vision or hearing occurs.
- Common side effects include headaches, flushing, and nasal congestion.
- Rarely can cause vision changes, such as blurred vision or color tinge.
- Serious side effects require immediate medical attention.
(5.4, 5.5)Pulmonary hypertension (PH) secondary to sickle cell disease: Sildenafil may cause serious vaso-occlusive crises. (5.8)ADVERSE REACTIONSDRUG INTERACTIONSUse with strong CYP3A inhibitors: Not recommended. (7, 12.3)Concomitant PDE-5 inhibitors: Avoid use with Viagra® or other PDE-5 inhibitors.
12.3 Pharmacokinetics
For pulmonary arterial hypertension:Take or administer the prescribed dose three times a day, four to six hours apart. Take or administer the prescribed dose three times a day, four to six hours apart. How to take sildenafil oral suspension for pulmonary hypertension:Please read and follow the Instructions for Use.Do not use the medicine if it’s still in powder form, doesn’t have a bottle adapter, or is missing an oral syringe. The pharmacist can provide a bottle adapter or oral syringe.Shake the bottle well for at least 10 seconds.Always measure the dose with the oral syringe provided in the package.Do not mix the dose with other liquids or flavorings.The person getting the medicine should be upright.Place the syringe in the mouth against the cheek. Push the plunger completely down.Wash the syringe with water and allow it to dry after each use.Store sildenafil oral suspension in the refrigerator.
Less Common but Serious Side Effects
Do not freeze.Throw away any unused medicine 60 days after receiving it from the pharmacist or on the expiration date written on the bottle’s label. How to take sildenafil oral suspension for pulmonary hypertension: Please read and follow the Instructions for Use. Please read and follow the Instructions for Use. Do not use the medicine if it’s still in powder form, doesn’t have a bottle adapter, or is missing an oral syringe. The pharmacist can provide a bottle adapter or oral syringe.
Related treatment guides
Shake the bottle well for at least 10 seconds. Always measure the dose with the oral syringe provided in the package. Do not mix the dose with other liquids or flavorings. The person getting the medicine should be upright. Place the syringe in the mouth against the cheek.