Get advice from one of our healthcare providers to learn more about your options. Don’t be tempted to use expired medicines.
| Contraindication | Rationale | Alternatives |
|---|---|---|
| Use with Nitrates | Risk of severe hypotension | consult physician for alternatives |
| Severe Liver Impairment | Altered drug metabolism | Dose adjustment or avoid use |
| Hypotension (<90/60 mmHg) | Potential for dangerously low blood pressure | monitor blood pressure |
| Recent Stroke or Heart Attack | Increased cardiovascular risk | Alternative therapies |
Gianmarco Troiano & Giacomo Lazzeri (2021) The potential toxic combination of grapefruit juice and sildenafil, Toxin Reviews, 40:3, 334-337. Sildenafil citrate induced retinal toxicity-electroretinogram, optical coherence tomography, and adaptive optics findings.
- Consult your doctor if you experience vision changes or ringing in ears.
- Sildenafil can interact with nitrates, causing dangerous hypotension.
- Use with caution if you have heart problems or low blood pressure.
- Report any persistent or painful erections lasting over 4 hours.
Do food and dose timing affect the efficacy of sildenafil? Hims & Hers has strict sourcing guidelines to ensure our content is accurate and current. We rely on peer-reviewed studies, academic research institutions, and medical associations. We strive to use primary sources and refrain from using tertiary references. Erectile dysfunction is a condition in which you have trouble getting or keeping an erection firm enough for satisfying sex. Erectile dysfunction affects as many as 30 million men in the United States. Premature ejaculation (PE) is a sexual dysfunction characterized by a short ejaculatory latency, a perceived lack of control about the timing of ejaculation, and distress and interpersonal difficulty related to ejaculating too quickly. Low testosterone or testosterone deficiency, also known as hypogonadism, is a condition in which patients develop symptoms such as low sex drive, erectile dysfunction (ED), and fatigue because the body doesn’t produce enough testosterone. Though many men don’t like to talk about it, ejaculation problems are very common. Some of the most common issues include premature, delayed, or retrograde ejaculation. Your pelvic floor is a lot like plumbing in your home: you never really think about it unless something goes wrong. When you think of male sexual dysfunction, concerns like erectile dysfunction (ED) or premature ejaculation (PE) probably come to mind first. But there’s another sex-related issue that’s more common in men than you might expect: difficulty orgasming. Sildenafil (Revatio, Viagra) is a generic prescription medication used to treat erectile dysfunction and pulmonary arterial hypertension in adults.
Brand names
That means you have to do a bit of sex planning when taking sildenafil. But you might be surprised at how sexy the anticipation can be—for you and your partner. Spend that time exploring new foreplay ideas or sharing your sexual fantasies. Avoid taking sildenafil if it’s expired. According to the FDA, you should skip taking any expired meds and safely dispose of them for the following reasons: Their chemical composition could be altered, making them unsafe to consume.
Allergic reaction
Their chemical composition could be altered, making them unsafe to consume. How can you tell if your medications are expired? Check the label for a date, likely next to the abbreviation “Exp.” Want more tips on how to get the most out of sildenafil? Read our guide on how to use Viagra for best results. It doesn’t really matter if you forget to take sildenafil because it’s designed for you to take it as you need it.
Regional issues
But be careful about accidentally doubling up on doses. Missing a dose before sex is no big deal, though doing so may impact the quality of your erection. However, forgetting you already took sildenafil and taking a subsequent dose within 24 hours can lead to complications, particularly if you go over 100 milligrams total. You should be aware of the potential side effects when taking any new drug. The most common side effects of sildenafil include: Most of these mild side effects will go away on their own as your body adapts to taking sildenafil. Sildenafil, which is also called sildenafil citrate, comes as an oral tablet. The drug also comes as an oral liquid suspension and IV infusion.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Kamagra Soft Tabs | 100mg | 180 + 8 Pills | 425.45€ 405.19€ | |
| Kamagra | 100mg | 84 + 6 Pills | 264.44€ 251.85€ | |
| Kamagra Oral Jelly | 100mg | 90 + 8 Sachets | 303.56€ 289.10€ | |
| Viagra Generic | 200mg | 90 + 6 Pills | 170.79€ 162.66€ | |
| Kamagra | 100mg | 120 + 6 Pills | 330.74€ 314.99€ | |
| Viagra Generic | 200mg | 20 Pills | 61.69€ 58.75€ | |
| Kamagra Soft Tabs | 100mg | 12 Pills | 57.55€ 54.81€ | |
| Viagra Generic | 50mg | 90 + 6 Pills | 107.37€ 102.26€ | |
| Viagra Generic | 200mg | 60 + 4 Pills | 125.19€ 119.23€ | |
| Kamagra Oral Jelly | 100mg | 10 Sachets | 54.55€ 51.95€ | |
| Kamagra Oral Jelly | 100mg | 63 + 7 Sachets | 224.18€ 213.50€ | |
| Viagra Generic | 25mg | 60 + 4 Pills | 71.99€ 68.56€ |
However, this article does not cover these forms. It only covers the side effects of sildenafil oral tablets. If you’d like to learn more about these forms, talk with your doctor. As with other drugs, sildenafil can cause side effects (adverse effects). It’s typically taken as a long-term treatment. Read on to learn about potential common, mild, and serious side effects. For a general overview of sildenafil, including details about its uses, refer to this article. Your doctor can also tell you more sildenafil 130mg about sildenafil. Sildenafil can cause certain side effects, some of which are more common than others. These side effects may be temporary, lasting a few days to weeks. However, if the side effects last longer than that, bother you, or become severe, be sure to talk with your doctor or pharmacist. These are just a few of the more common side effects reported by people who took sildenafil in clinical trials:* * To learn more about the clinical trials of sildenafil, refer to the drug’s prescribing information for erectile dysfunction and pulmonary arterial hypertension. † For more information about this side effect, see “Sildenafil: Side effect specifics” below.
- Sildenafil 25 mg has a rapid onset compared to higher doses.
- It is considered effective for most men with mild to moderate ED.
- Alcohol intake can reduce the effectiveness of the medication.
- The medication is generally safe when used as directed by a healthcare provider.
Optum Perks is owned by RVO Health. By clicking on this link, we may receive a commission. Mild side effects can occur with sildenafil use. This list doesn’t include all possible mild side effects of the drug.
| Side Effect | Incidence | Severity | Management Suggestions |
|---|---|---|---|
| Headache | Common | Mild to moderate | Take pain relievers |
| Flushing | Common | Mild | Cool compress, hydration |
| Dizziness | Common | Mild | Sit or lie down immediately |
| Nasal Congestion | Less common | Mild | Use decongestants if needed |
| Visual Disturbances | Rare | Mild | Discontinue and consult doctor |
For more information, you can refer to sildenafil’s prescribing information for erectile dysfunction (ED) and pulmonary arterial hypertension (PAH). Mild side effects that have been reported with sildenafil include: These side effects may be temporary, lasting a few days to weeks. Note: After the Food and Drug Administration (FDA) approves a drug, it tracks and reviews side effects of the medication.
8.6 Renal Impairment
But sildenafil also comes with some more rare but potentially serious side effects like: Sudden loss of vision (potentially a sign of non-arteritic anterior ischemic optic neuropathy or NAION) Sudden loss of vision (potentially a sign of non-arteritic anterior ischemic optic neuropathy or NAION) Priapism (a painful erection lasting longer than four hours) Priapism (a painful erection lasting longer than four hours) If you experience any of these symptoms after taking sildenafil, seek immediate medical attention. And FYI: Even mild side effects can impact your life. If you get an upset stomach every time you take sildenafil, talk with a healthcare professional. They may recommend changing your dose or switching medications altogether. Read more about potential sildenafil reactions in our sildenafil side effects guide.
What’s the difference between sildenafil 50 mg and 100 mg?
It might be dangerous to use sildenafil if you have certain medical conditions or take specific drugs. If your healthcare provider told you not to engage in sexual activity because of a heart condition (like a history of heart attack; heart disease; heart failure; angina; or arrhythmia, also known as an irregular heartbeat), it’s probably best to abstain from having sex and taking sildenafil. Using sildenafil when you take medicines for high blood pressure or pulmonary arterial hypertension could cause a dangerous, potentially life-threatening dip in blood pressure. Avoid taking sildenafil with nitrates (medications for chest pain) such as isosorbide dinitrate, isosorbide mononitrate, nitroglycerin, and alpha-blockers or other blood pressure medications like riociguat. If you have a condition that puts you at higher risk of priapism—like sickle cell anemia, leukemia, Peyronie’s disease, or multiple myeloma—you should avoid sildenafil.
Does sildenafil cause different side effects in females?
There isn’t enough data to say whether sildenafil is safe for people with this eye condition. Sildenafil can interact with the nitrites found in certain recreational drugs popularly known as “poppers,” causing a dangerous drop in blood pressure. Don’t mix sildenafil with other ED drugs, like Cialis®, Levitra®, Revatio® (another brand name for sildenafil) or Stendra®. This can put you at risk for low blood pressure. More of something isn’t always better! If you develop a side effect while taking sildenafil and want to tell the FDA about it, visit MedWatch. * For more information about this side effect, see “Sildenafil: Side effect specifics” below. † An allergic reaction is possible after taking sildenafil.
Further information
Aside from heart medications and other PDE5 inhibitors, taking sildenafil with ritonavir, ketoconazole, itraconazole, or clarithromycin (an antibiotic) can increase the concentration of sildenafil in your body and make you more likely to experience side effects. Talk with a healthcare professional before mixing sildenafil with over-the-counter supplements, which aren’t regulated in the same way as prescription drugs. Learn more about health and drug interactions in our sildenafil sildenafil pink pill interactions guide. If you’re living with ED symptoms, you’re not alone. Sildenafil can make it easier to get and keep an erection so you can enjoy a fulfilling sex life.
Pulmonary hypertension
Here’s what to remember when taking sildenafil for ED: Take it at least 30 to 60 minutes and no more than four hours before sexual stimulation. Also, avoid high-fat foods or meals that can slow absorption. Take it at least 30 to 60 minutes and no more than four hours before sexual stimulation. Don’t mix sildenafil with medications that can cause dangerous interactions. Unsure whether your meds are safe to combine with sildenafil? However, this side effect was rarely reported in clinical trials of sildenafil for ED and PAH.
- Sildenafil 25 mg is a lower dose suitable for sensitive individuals.
- It may be prescribed for pulmonary arterial hypertension as well.
- The medication can be taken with or without food.
- Do not crush or chew the tablets; swallow whole.
To learn more, see the “Sildenafil: Side effect specifics” section below. The list below may not include all possible serious side effects of the drug.
2.3 Dosage Adjustments in Specific Situations
Regular exercise, a balanced diet, and quality sleep can maximize your overall health and sexual well-being. Consider alternative treatments if sildenafil doesn’t work for you. Other oral erectile dysfunction medications include tadalafil (generic for Cialis), avanafil (Stendra), vardenafil, and chewable Hard Mints. Your healthcare provider might also recommend adjusting your sildenafil dosage. Ready to find an erectile dysfunction treatment that works for you? If you develop serious side effects while taking sildenafil, call your doctor right away. If the side effects seem life threatening or you think you’re having a medical emergency, immediately call 911 or your local emergency number.
| Condition | Patient Group | Recommended Dose | Notes |
|---|---|---|---|
| Erectile Dysfunction | Men over 18 | 25-50 mg | As needed before activity |
| Pulmonary Arterial Hypertension | Adults with PAH | 25 mg | Under medical supervision |
| Altitude Sickness Prevention | High altitude travelers | 25 mg | Off-label use |
Serious side effects that have been reported and their symptoms include: Symptoms can include:tinnitus (ringing in your ear)dizzinessdecrease in hearing Symptoms can include:trouble seeing in either eyeblurry visionseeing eye floaters * To learn more about this side effect, see the “Sildenafil: Side effect specifics” section below.
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